Cookie policy

This website www.iridiumce.com uses Cookies and similar technologies in order to distinguish you from other users. By using Cookies, We are able to provide you with a better experience and to improve Our Site by better understanding how you use it. Please read this Cookie Policy carefully and ensure that you understand it. Your acceptance of Our Cookie Policy is deemed to occur when you press the “accept” button on Our Cookie banner or when you have selected your preferred Cookie options in Our Cookie manager and pressed the “Continue” button. If you do not agree to Our Cookie Policy, please stop using Our Site immediately.

In this Cookie Policy, unless the context otherwise requires, the following expressions have the following meanings:

Cookie: means a small file placed on your computer or device by Our Site when you visit certain parts of Our Site and/or when you use certain features of Our Site;

Cookie Law: means the relevant parts of the Privacy and Electronic Communications (EC Directive) Regulations 2003 and of EU Regulation 2016/679 General Data Protection Regulation (“GDPR”);

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3.1 Our Site may place and access certain first-party Cookies on your computer or device. First party Cookies are those placed directly by Us and are used only by Us. We use Cookies to facilitate and improve your experience of Our Site and services. We have carefully chosen these Cookies and have taken steps to ensure that your privacy and personal data is protected and respected at all times.
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3.3 All Cookies used by and on Our Site are used in accordance with current Cookie Law. We may use some or all of the following types of Cookie:

3.3.1 Strictly Necessary Cookies
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3.3.5 Third Party Cookies
Third-party Cookies are not placed by Us; instead, they are placed by third parties that provide services to Us and/or to you. Third-party Cookies may be used by advertising services to serve up tailored advertising to you on Our Site, or by third parties providing analytics services to Us (these Cookies will work in the same way as analytics Cookies described above).
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Any of the above types of Cookie may be a persistent Cookie. Persistent Cookies are those which remain on your computer or device for a predetermined period and are activated each time you visit Our Site.
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Name of Cookie	Provider	Purpose	Expires
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cookiesEnabled	checkout.stripe.com	Used to process payments for our website.	When you close your browser
__stripe_sid	checkout.stripe.com	Used to process payments for our website.	When you close your browser
__stripe_mid	checkout.stripe.com	Used to distinguish users.	1 year
ab_disable_remember_	checkout.stripe.com	Used to process payments for our website.	7 years
checkout-test-session	checkout.stripe.com	Used to process payments for our website.	10 years
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vuid	vimeo.com	These cookies are used by Vimeo to collect analytics tracking information.	1 year
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wcsid	www.iridiumce.com	a session identifier that we use only on your site to keep track of a single chat session	When you close your browser
olfsk	www.iridiumce.com	storage identifier that we use to maintain chat state across pages (e.g. message history)	2 years
_okbk	www.iridiumce.com	extra state information (e.g. chat box being open/closed)	When you close your browser
_ok	www.iridiumce.com	most recent Olark site ID (security measure)	When you close your browser
_oklv	www.iridiumce.com	the Olark loader version (for improved caching)	When you close your browser
_okla	www.iridiumce.com	used for caching purposes (loaded from CDN vs. loaded from our infrastructure)	When you close your browser
_okgid	www.iridiumce.com	used for caching by setting a hash for assets to determine if they have changed and if they need to be refreshed	When you close your browser
_okac	www.iridiumce.com	used for caching by setting a hash for assets to determine if they have changed and if they need to be refreshed	When you close your browser

Name of Cookie	Provider	Purpose	Expires
pubsub_cookie	www.iridiumce.com	This cookie is used for the freshchat service	When you close your browser
hop-	www.iridiumce.com	This cookie is used for the freshchat service	When you close your browser
	www.iridiumce.com	This cookie is used for the freshchat service	When you close your browser
_	www.iridiumce.com	This cookie is used for the freshchat service	1 year
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Name of Cookie	Provider	Purpose	Expires
ZD-referrerPolicy	www.iridiumce.com	Stores referrer tags	Forever
ZD-zE_oauth	www.iridiumce.com	Stores the authentication token once the user has been authenticated.	2 hours
ZD-currentTime	www.iridiumce.com	Sets the time when page loads.	Forever
ZD-settings	www.iridiumce.com	Stores a hash of settings so that we don't keep sending blips after the initial one	Forever
ZD-suid	www.iridiumce.com	Session id for pathfinder.	20 minutes
ZD-buid	www.iridiumce.com	Collects Machine ID.	Forever

4.4 Our Site uses analytics services provided by your analytics services, if any. Website analytics refers to a set of tools used to collect and analyse anonymous usage information, enabling us to better understand how Our Site is used. This, in turn, enables us to improve Our Site and the products and services offered through them.
4.5 The analytics services used by Our Site use Cookies to gather the required information. You do not have to allow us to use these Cookies, however, whilst our use of them does not pose any risk to your privacy or your safe use of Our Site, it does enable us to continually improve Our Site, making it a better and more useful experience for you.
4.6 The analytics services used by Our Site uses the following Cookies (remove cookies not exploited in your school):

Name of Cookie	Provider	Purpose	Expires
_ga	www.iridiumce.com	Google Analytics: Registers a unique ID that is used to generate statistical data on how the visitor uses the website.	2 years
_gat	www.iridiumce.com	Google Analytics: Used by Google Analytics to throttle the request rate.	When you close your browser
_gid	www.iridiumce.com	Google Analytics: Registers a unique ID that is used to generate statistical data on how the visitor uses the website.	When you close your browser
collect	www.iridiumce.com	Google Analytics: Used to send data to Google Analytics about the visitor's device and behaviour. Tracks the visitor across devices and marketing channels.	When you close your browser

Name of Cookie	Provider	Purpose	Expires
__smToken	www.iridiumce.com	The __smToken is set once you login to Sumo and is checked to verify whether you are logged into Sumo or not.	1 year
__smSmartbarShown	www.iridiumce.com	Is set when the Smartbar is shown	50 years
__smVID	www.iridiumce.com	Used to display relevant advertising	1 month
__smSessionId	www.iridiumce.com	Used by Sumo to establish a cookie on a users computer to begin a session to enable Sumo products	When you close your browser

4.7 Targeting/Marketing cookies
Targeting/Marketing cookies are used to track visitors across websites. They may be used by those companies to build a profile of your interests and show you relevant adverts on other sites. They do not store directly personal information but are based on uniquely identifying your browser and internet device. The intention is to display ads that are relevant and engaging for the individual user and thereby more valuable for publishers and third-party advertisers. If you do not allow these cookies, you will experience less targeted advertising (remove cookies not exploited in your school):

Name of Cookie	Provider	Purpose	Expires
__hstc	www.iridiumce.com	The main cookie for tracking visitors. It contains the domain, utk (see below), initial timestamp (first visit), last timestamp (last visit), current timestamp (this visit), and session number (increments for each subsequent session).	2 years
hubspotutk	www.iridiumce.com	This cookie is used for to keep track of a visitor's identity. This cookie is passed to HubSpot on form submission and used when de-duplicating contacts.	10 years
__hssc	www.iridiumce.com	This cookie keeps track of sessions. This is used to determine if we should increment the session number and timestamps in the __hstc cookie. It contains the domain, viewCount (increments each pageView in a session), and session start timestamp.	30 min
__hssrc	www.iridiumce.com	Whenever HubSpot changes the session cookie, this cookie is also set. We set it to 1 and use it to determine if the visitor has restarted their browser. If this cookie does not exist when we manage cookies, we assume it is a new session.	session
messagesUtk	www.iridiumce.com	This cookie is used to recognize visitors who chat with you via the messages tool. If the visitor leaves your site before they're added as a contact, they will have this cookie associated with their browser. If you have a history of chatting with a visitor and they return to your site later in the same cookied browser, the messages tool will load your conversation history with that visitor.	session

(Keep section 5.1 and 5.2 if you are using our cookie opt-in mechanism from School Privacy settings.)

5.1 Before Cookies are placed on your computer or device, you will be shown a banner requesting your consent to set those Cookies. By giving your consent to the placing of Cookies you are enabling Us to provide the best possible experience and service to you. You may, if you wish, deny consent to the placing of Cookies unless those Cookies are strictly necessary; however certain features of Our Site may not function fully or as intended. You will be given the opportunity to allow and/or deny different categories of Cookie that We use.
5.2 In addition to the controls that We provide, you can choose to enable or disable Cookies in your internet browser. Most internet browsers also enable you to choose whether you wish to disable all Cookies or only third-party Cookies. By default, most internet browsers accept Cookies but this can be changed. For further details, please consult the help menu in your internet browser or the documentation that came with your device.
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Overview

Learning Objectives

CME/ Information

Faculty and Disclosures

Instructions

AI Statement

Upon completion of this activity, the participant should be able to:

Identify the full NT1 symptom pentad and the systemic clinical burden of orexin deficiency.
Apply the cataplexy interrogation question at the CPAP non-response encounter.
Differentiate NT1 from NT2, idiopathic hypersomnia, and common misdiagnoses using the defining diagnostic criterion of cataplexy or CSF hypocretin-1 <110 pg/mL.
Distinguish NT1 from medication-induced and primary psychiatric EDS using ICSD-3 criteria when psychiatric comorbidity complicates evaluation of excessive daytime sleepiness.
Apply evidence-based PSG/MSLT diagnostic protocols, including medication washout requirements, SOREMP interpretation, and CSF hypocretin-1 <110 pg/mL as a standalone NT1 diagnostic criterion per ICSD-3.
Integrate SDoH-informed screening, navigator referral pathways, and telehealth-compatible approaches to reduce diagnostic delay in NT1 across diverse patient populations.
Individualize NT1 treatment selection using an SDM framework informed by the limitations of current pharmacotherapy and the mechanism of emerging OX2R-directed therapies.

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global and Iridium CE do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Global adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by Joint Accreditation and all other accrediting bodies, as applicable, stating those activities where CE credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited CE program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months. All financial relationships reported are appropriately identified as relevant by Global. All relevant financial relationships have been mitigated in advance of delivery of the activity to learners.

All relevant financial relationships have been mitigated.

The faculty have the following relevant financial relationships with ineligible companies:

Professor of Psychiatry and Behavioral Sciences (Sleep

Medicine)

Chief of the Stanford Division of Sleep Medicine

Medical Director of the Stanford Sleep Medicine Center

Associate Chair and Professor in the Stanford Department of

Psychiatry and Behavioral Sciences at the Stanford

University Medical Center,

Director of the Stanford Human Sleep Research Laboratory

Disclosures

Consulting Fee (e.g., Advisory Board): Avadel Pharmaceuticals, SoundHealth Inc.. Alkermes, Lilly, Lundbeck, Apnimed, Eisai

Contracted Research (Principal Investigators must provide information, even if received by the institution): Samsung

Stock Shareholder (Individual stocks/Stock options; diversified mutual funds do not need to be disclosed): Vivos Therapeutics

Stock Option Holder (Individual stocks/Stock options; diversified mutual funds do not need to be disclosed): Asleep, SoundHealth Inc.

Narcolepsy Type 1 (NT1) remains substantially underrecognized, resulting in significant diagnostic delays and missed opportunities for timely treatment. This educational activity combines expert faculty presentations, a patient perspective, and an interactive AI-powered patient simulation to strengthen clinicians' ability to recognize NT1, apply evidence-based diagnostic strategies, address barriers to care, and integrate emerging therapies into patient-centered management. Through realistic clinical scenarios and practical discussion, participants will gain strategies to improve diagnostic accuracy and optimize outcomes for patients with NT1.

The simulated patient responds only within a case written and approved by the activity faculty, Clete A. Kushida, MD, PhD, and Atul Malhotra, MD. Clinical content is limited to a closed set of sources: current clinical guidelines and the references cited in the activity slides (see the reference list), current as of October 12, 2026.

The AI does not search the internet. It does not give you diagnostic or treatment recommendations. Before release, the faculty and the IridiumCE and Global Education Group planners, tested the simulation for accuracy, completeness, balance and freedom from commercial bias on October 12, 2026.

Platform: Patient dialogue is generated using OpenAI's GPT-4.1 model (gpt-4.1-2025-04-14). The patient's video avatar is powered by HeyGen.

Independence. Global, as the accredited provider, is responsible for all content in this activity, including what the AI generates.

This activity is supported by an independent educational grant from Takeda Pharmaceuticals U.S.A., Inc. Takeda had no role in writing the case, configuring the AI, or deciding how it is scored. Scores reflect your clinical reasoning and communication, not which treatment is chosen. No product advertising is provided within activity.

Limitations. AI can make mistakes. Responses may occasionally be incomplete, worded unexpectedly, or wrong. Known limitations for this case, e.g. the patient cannot respond to physical-exam maneuvers outside the menu. This simulation is for educational purposes only and is not clinical guidance. The learners remain responsible for their own clinical decisions. If a response seems inaccurate or inappropriate, select Flag.

A clinical reviewer will review it.

Data. All conversation and scores are recorded so we can give personalized feedback, award credit, and evaluate and improve the activity.

Transcripts are stored apart from your name and analyzed in de-identified form. Iridium Continuing Education holds the transcripts in secure, access-controlled systems.

Learner data is never sold, never shared with commercial supporters except as aggregate de-identified results, and never used to train outside AI models.

Your voice is used only to transcribe your words. Your voice is never copied, cloned or used to create a synthetic voice. Please do not enter information about real patients.

Compliance. This use of AI follows the Accreditation Council for Continuing Medical Education (ACCME) Guidance on the Responsible Use of Artificial Intelligence in Accredited Continuing Education (January 30, 2026) and its Urgent Alert on the Use of AI in Accredited CE (April 14, 2026). It also meets the ACCME Standards for Integrity and Independence in Accredited Continuing Education.

Questions? Contact info@iridiumce.com.

Name of Cookie	Purpose	Strictly Necessary	Expires
XSRF-TOKEN	Preserves User Login information and states	Yes	When you close your browser
DPSettings	Preserves the user's Cookie policy preferences	Yes	12 days
slim_session	Preserves User Login information and states	Yes	1 day

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ci_session	refersion.com	Preserves users states across page requests.	When you close your browser
refersion_csrf_code	refersion.com	Sets csrf token to prevent cross site request forgery.	When you close your browser
__cfduid	refersion.com	Used by the content network, Cloudflare, to identify trusted web traffic.	1 year

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